Q. What is the likelyhood that is closest for developement of malignant changes in below patient ?
1. 30-40%
2. upto 1%
3. 3-4%
4. None
Answer -
The picture depicts multiple knobby bony protuberances in femur and tibia metaphyses and thus suggestive of a case with HME (Hereditary Multiple Exostoses).
The chances of malignant transformation ( into Chondrosarcoma) are approximately as follows -
Solitaru osteochondroma - upto 1%
HME - 2-4%
Multiple Enchondroma (Ollier disease) or Maffuci Syndrome (i.e enchondroma with various hemangioma) have higher chances - 10-40%
1. 30-40%
2. upto 1%
3. 3-4%
4. None
Answer -
The picture depicts multiple knobby bony protuberances in femur and tibia metaphyses and thus suggestive of a case with HME (Hereditary Multiple Exostoses).
The chances of malignant transformation ( into Chondrosarcoma) are approximately as follows -
Solitaru osteochondroma - upto 1%
HME - 2-4%
Multiple Enchondroma (Ollier disease) or Maffuci Syndrome (i.e enchondroma with various hemangioma) have higher chances - 10-40%
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